Journal Publications:

back home

  1. P. Christen, B. van Rietbergen, F. M. Lambers, R. Müller, and K. Ito. Bone morphology allows estimation of loading history in a murine model of bone adaptation. Biomechanics and Modeling in Mechanobiology, 11(3-4):483-492, 2012.
  2. P. Christen, K. Ito, R. Müller, M. R. Rubin, D. W. Dempster, J. P. Bilezikian, and B. van Rietbergen. Patient-specific bone modelling and remodelling simulation of hypoparathyroidism based on human iliac crest biopsies. Journal of Biomechanics, 45(14):2411-2416, 2012.
  3. P. Christen, K. Ito, I. Knippels, R. Müller, G. H. van Lenthe, and B. van Rietbergen. Subject-specific bone loading estimation in the human distal radius. Journal of Biomechanics, 46(4):759-766, 2013.
  4. P. Christen, K. Ito, A. A. Dos Santos, R. Müller, and B. van Rietbergen. Validation of a bone loading estimation algorithm for patient-specific bone remodeling simulations. Journal of Biomechanics, 46(5):941-948, 2013.
  5. R. Ellouz, R. Chapurlat, B. van Rietbergen, P. Christen, J. B. Pialat, and S. Boutroy. Challenges in longitudinal measurements with HR-pQCT: Evaluation of 3D registration method to improve bone microarchitecture and strength reproducibility. Bone, 63:147-157, 2014.
  6. P. Christen, K. Ito, F. Galis, and B. van Rietbergen. Determination of hip-joint loading patterns of living and extinct mammals using an inverse Wolff's law approach. Biomechanics and Modeling in Mechanobiology, 14(2):427-432, 2015.
  7. P. Christen, K. Ito, R. Ellouz, S. Boutroy, E. Sornay-Rendu, R. D. Chapurlat, and B. van Rietbergen. Bone remodelling in humans is load-driven but not lazy. Nature Communications, 5:4855, doi:10.1038/ncomms5855, 2014.
  8. P. Christen, K. Ito, and B. van Rietbergen. A potential mechanism for allometric trabecular bone scaling in terrestrial mammals. Journal of Anatomy, 226(3):236-243, 2015.
  9. P. Christen, F. A. Schulte, A. Zwahlen, B. van Rietbergen, S. Boutroy, L. J. Melton III, S. Amin, S. Khosla, J. Goldhahn, and R. Müller. Voxel size dependency, reproducibility, and sensitivity of an in vivo bone loading estimation algorithm. Journal of The Royal Society Interface, 13(114), doi:10.1098/rsif.2015.0991, 2016.
  10. S. D. Badilatti, P. Christen, A. Levchuk, J. H. Marangalou, B. van Rietbergen, and R. Müller. Large-scale microstructural simulation of load-adaptive bone remodeling in whole human vertebrae. Biomechanics and Modeling in Mechanobiology, 15(1):83-95, 2016.
  11. N. Ohs, F. Keller, O. Blank, W.-Y. W. Lee, C.-Y. J. Cheng, P. Arbenz, R. Müller, and P. Christen. Towards in silico prognosis using big data. Current Directions in Biomedical Engineering, 2(1):57-60, 2016.
  12. S. D. Badilatti, P. Christen, I. Parkinson, and R. Müller. Load-adaptive bone remodeling simulations reveal osteoporotic microstructural and mechanical changes in whole human vertebrae. Journal of Biomechanics, 49(16):3770-3779, 2016.
  13. S. D. Badilatti, P. Christen, Stephen J. Ferguson, and R. Müller. Computational modeling of long-term effects of prophylactic vertebroplasty on bone adaptation. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 231(5):423-431, 2017.
  14. J. A. Steiner, P. Christen, R. Affentranger, S. J. Ferguson, and G. H. van Lenthe. A novel in silico method to quantify primary stability of screws in trabecular bone. Journal of Orthopaedic Research, 35(11):2415-2424, 2017.
  15. J. J. A. de Jong, P. Christen, S. Boutroy, P. P. Geusens, J. P. W. van den Bergh, R. Müller, and B. van Rietbergen. Feasibility of rigid 3D image registration of high-resolution peripheral quantitative computed tomography images of healing distal radius fractures. PLOS ONE, 12(7), 2017.
  16. P. Christen, S. Boutroy, R. Ellouz, R. Chapurlat, and B. van Rietbergen. Least-detectable and age-related local in vivo bone remodelling assessed by time-lapse HR-pQCT. PLOS ONE, 13(1), 2018.
  17. J. A. Steiner, U. Hofmann, P. Christen, J. Favre, S. J. Ferguson, and G. H. van Lenthe. Patient-specific in silico models can quantify primary implant stability in elderly human bone. Journal of Orthopaedic Research, 36(3):954-962, 2018.
  18. F. A. Schulte, P. Christen, S. D. Badilatti, I. Parkinson, S. Khosla, J. Goldhahn, and R. Müller. Virtual supersampling as post-processing step preserves the trabecular bone morphometry in human peripheral quantitative computed tomography scans. PLOS ONE, 2019.
  19. D. C. Tourolle né Betts, E. Wehrle, G. Paul, G. Kuhn, P. Christen, S. Hofmann, and R. Müller. The association between mineralised tissue formation and the mechanical local in vivo environment: Time-lapsed quantification of a mouse defect healing model. Scientific Reports, 10(1100), 2020.
  20. L. Engelhardt, M. Melzner, L. Havelkova, P. Fiala, P. Christen, S. Dendorfer, and U. Simon. A new musculoskeletal AnyBodyTM detailed hand model. Computer Methods in Biomechanics and Biomedical Engineering, 24(7):777-787, 2021.
  21. J. Zhang, Y. Wang, K. L. Cheng, K. Cheuk, T. P. Lam, A. L. H. Hung, J. C. Y. Cheng, Y. Qiu, R. Müller, P. Christen, and W. Y. W. Lee. Association of higher bone turnover with risk of curve progression in Adolescent Idiopathic Scoliosis. Bone, 143:115655, 2021.
  22. L. Engelhardt, F. Niemeyer, P. Christen, R. Müller, K. Stock, M. Blauth, K. Urban, A. Ignatius, and U. Simon. Simulating metaphyseal fracture healing in the distal radius. Biomechanics, 1(1):29-42, 2021.
  23. N. Ohs, C. J. Collins, D. C. Tourolle né Betts, P. R. Atkins, B. Schroeder, M. Blauth, P. Christen, and R. Müller. Automated segmentation of fractured distal radii by 3D geodesic active contouring of in vivo HR-pQCT images. Bone, 147:115930, 2021.
  24. P. R. Atkins, K. Stock, N. Ohs, C. J. Collins, L. Horling, S. Benedikt, G. Degenhart, K. Lippuner, M. Blauth, P. Christen, and R. Müller. Formation Dominates Resorption With Increasing Mineralized Density and Time Postfracture in Cortical but Not Trabecular Bone: A Longitudinal HRpQCT Imaging Study in the Distal Radius. JBMR Plus, 5(6):e10493, 2021.
  25. S. Fix, T. Probst, O. Ruggli, T. Hanne, and P. Christen. Automatic Programming As An Open-Ended Evolutionary System. International Journal of Computer Information Systems and Industrial Management Applications, 14:204-212, 2022.
  26. P. Christen. System Metamodelling of Open-Ended Evolution Implemented with Self-Modifying Code. Complex Systems, 32(4):353-380, 2024.
  27. D. E. Whittier, M. Walle, P. R. Atkins, C. J. Collins, M. A. Zumstein, P. Christen, K. Lippuner, and R. Müller. Structural alterations during fracture healing lead to void spaces developing in surrounding bone microarchitecture. Journal of Bone and Mineral Research, 40(6):791-798, 2025.

Reviews and Editorials:

  1. P. Christen and R. Müller. In vivo high-resolution computed tomography assessment of bone remodelling and its mechanoregulation. Current Osteoporosis Reports, 15(4):311-317, 2017.
  2. P. Christen. Moving beyond the genome with computer modelling. Personalized Medicine, 15(3):145-148, 2018.